HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-dichloro-4-(trifluoromethyl)benzoic Acid → cis-2,6-Dichloro-N-(2-pyrrolidin-1-yl-cyclopentyl)-4-trifluoromethyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-dichloro-4-(trifluoromethyl)benzoic Acid | HCID 11680460 | — |
| Reactant | cis-2-Pyrrolidin-1-yl-cyclopentylamine | HCID 30820884 | — |
| Product | cis-2,6-Dichloro-N-(2-pyrrolidin-1-yl-cyclopentyl)-4-trifluoromethyl-benzamide | HCID 51001232 | — |
Reaction Steps
The title compound, white solid, MS: m/e=395.1 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclopentylamine (intermediate Q) and 2,6-dichloro-4-trifluoromethyl-benzoic acid (intermediate Y).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08080541B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-88d482be3d9a4252804837fc8a3eedf1 |
| Source note | uspto-grants-2011_12 |