HuagongsheHuagongshe Chemistry Print Report · For research reference only
cis-2-Pyrrolidin-1-yl-cyclopentylamine → 2-Isopropyl-N-((1SR,2RS)-2-pyrrolidin-1-yl-cyclopentyl)-4-trifluoromethyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | cis-2-Pyrrolidin-1-yl-cyclopentylamine | HCID 30820884 | — |
| Reactant | 2-Isopropyl-4-trifluoromethyl-benzoic acid | HCID 59438540 | — |
| Product | 2-Isopropyl-N-((1SR,2RS)-2-pyrrolidin-1-yl-cyclopentyl)-4-trifluoromethyl-benzamide | HCID 66682106 | — |
Reaction Steps
The title compound, orange solid, MS: m/e=369.2 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclopentylamine (intermediate Q) and 2-isopropyl-4-trifluoromethyl-benzoic acid (intermediate AH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08080541B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-7621a5a5b0b04354b5117078535cead1 |
| Source note | uspto-grants-2011_12 |