1,4-Dibromobutane → HCID 66681156, compound

HRID 659296Notes

Reaction equation

HRID 659296 reaction equation
[NH2:1][CH:2]1[CH2:4][CH:3]1[NH:5][C:6](=[O:21])[C:7]1[C:12]([S:13][CH3:14])=[CH:11][C:10]([C:15]([F:18])([F:17])[F:16])=[CH:9][C:8]=1[O:19][CH3:20].Br[CH2:23][CH2:24][CH2:25][CH2:26]Br>>[CH3:20][O:19][C:8]1[CH:9]=[C:10]([C:15]([F:17])([F:18])[F:16])[CH:11]=[C:12]([S:13][CH3:14])[C:7]=1[C:6]([NH:5][CH:3]1[CH2:4][CH:2]1[N:1]1[CH2:26][CH2:25][CH2:24][CH2:23]1)=[O:21]

Participants

3

Reactant 2

HCID 80561,4-DibromobutaneHCID 66681582HCID 66681582, compound

Product 1

HCID 66681156HCID 66681156, compound

Procedure

The title compound, light yellow solid, MS: m/e=375.2 [(M+H)+], was prepared in accordance with the general method of example 10 from N-((1SR,2RS)-2-amino-cyclopropyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamide (intermediate AC) and 1,4-dibromobutane.

Sources & evidence

ORD record
ord-3cf36a0511514431b1c9a7fd4ae79261
Source dataset
uspto-grants-2011_12
Patent number
US08080541B2

Reaction notes

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