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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 659303생성일: 2026년 10월 25일

2-Cyclopropyl-4,6-bis-trifluoromethyl-benzoic acid → 2-Cyclopropyl-N-((cis)-2-pyrrolidin-1-yl-cyclohexyl)-4,6-bis-trifluoromethyl-benzamide

https://huagongshe.com/reaction/659303

반응식

참여 물질

역할이름HCID투입량
반응물2-Cyclopropyl-4,6-bis-trifluoromethyl-benzoic acidHCID 58167765—
반응물cis-2-Pyrrolidin-1-yl-cyclohexylamine dihydrochlorideHCID 66680564—
생성물2-Cyclopropyl-N-((cis)-2-pyrrolidin-1-yl-cyclohexyl)-4,6-bis-trifluoromethyl-benzamideHCID 51001328—

반응 단계

The title compound, white solid, MS: m/e=449.3 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclohexylamine dihydrochloride (intermediate F) and 2-cyclopropyl-4,6-bis-trifluoromethyl-benzoic acid (intermediate AN).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08080541B2
출처 데이터셋uspto-grants-2011_12
ORD IDord-294afdd55473481ea83bac75f9291707
출처 메모uspto-grants-2011_12