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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 659304Generated: October 25, 2026

cis-2-Pyrrolidin-1-yl-cyclopentylamine → 2-Ethyl-N-((cis)-2-pyrrolidin-1-yl-cyclopentyl)-4,6-bis-trifluoromethyl-benzamide

https://huagongshe.com/reaction/659304

Reaction equation

Participants

RoleNameHCIDCharge
Reactantcis-2-Pyrrolidin-1-yl-cyclopentylamineHCID 30820884—
Reactant2-Ethyl-4,6-bis-trifluoromethyl-benzoic acidHCID 59197934—
Product2-Ethyl-N-((cis)-2-pyrrolidin-1-yl-cyclopentyl)-4,6-bis-trifluoromethyl-benzamideHCID 51001329—

Reaction Steps

The title compound, white solid, MS: m/e=423.3 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclopentylamine (intermediate Q) and 2-ethyl-4,6-bis-trifluoromethyl-benzoic acid (intermediate AO).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08080541B2
Source datasetuspto-grants-2011_12
ORD IDord-6f80cac067614139800439e00662e322
Source noteuspto-grants-2011_12