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HRID659327

反应详情

EQUATION

反应方程式

HRID 659327 的结构方程式

REACTANTS

反应物

2
结构：CS(=O)(=O)c1ccc(B(O)O)cc1
HCID2734364

4-(Methylsulfonyl)phenylboronic acid

C7H9BO4S

结构：O=C1CNc2ncc(I)cc2N1Cc1ccccc1
HCID57885979

3,4-Dihydro-7-iodo-1-(phenylmethyl)pyrido[2,3-b]pyrazin-2(1H)-one

C14H12IN3O

PRODUCTS

生成物

1
结构：CS(=O)(=O)c1ccc(-c2cnc3c(c2)N(Cc2ccccc2)C(=O)CN3)cc1
HCID24852571

未命名化合物

收率 43%

PROCEDURE

实验过程

1-Benzyl-7-iodo-3,4-dihydro-1H-pyrido[2,3-b]pyrazin-2-one (46 mg) was reacted with 4-(methanesulfonyl)phenyl boronic acid as in General Procedure 4B to give the title compound as a yellow solid (43% yield). LCMS: m/z=394.22 (M+H+), 1H-NMR (CDCl3, 400 MHz) δ 3.08 (3H, s), 4.54 (2H, s), 5.28 (2H, s), 7.30 (3H, m), 7.39 (3H, m), 7.45 (2H, d, J=8.3 Hz), 7.78 (1H, d, J=1.5 Hz), 7.94 (2H, d, J=8.3 Hz).