HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzylamine → 6-Benzylsulfamoyl-5-chloro-1-indanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 6-chloro-3-oxo-2,3-dihydro-1H-indene-5-sulfonyl chloride | HCID 22119034 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 6-Benzylsulfamoyl-5-chloro-1-indanone | HCID 22756372 | — |
Reaction Steps
According to Example 2(a), 13.26 g (50 mmoles) of 5-chloro-6-chlorosulfonyl-1-indanone, 5.89 g (55 mmoles) of benzylamine and 5.05 g (50 mmoes) of triethylamine in a total of 100 ml of acetone yield 6-benzylsulfamoyl-5-chloro-1-indanone having a melting point of 203° to 205° C., from which the pure product is obtained after a recrystallization from ethanol, said product having a melting point of 228° to 231° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04129656 |
| Source dataset | uspto-grants-1978_12 |
| ORD ID | ord-15a3f7e70a6c42b98b373c3e0d666fde |
| Source note | uspto-grants-1978_12 |