4-(Piperazin-1-yl)furo[3,2-c]pyridine → (3-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}phenyl)-(4-furo[3,2-c]pyridin-4-ylpiperazin-1-yl)methanone

Participants

Role	Name	HCID	Charge
Reactant	4-(Piperazin-1-yl)furo[3,2-c]pyridine	HCID 2794808	—
Reactant	3-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid	HCID 58327807	—
Product	(3-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}phenyl)-(4-furo[3,2-c]pyridin-4-ylpiperazin-1-yl)methanone	HCID 58327801	—

Reaction Steps

3-{1-[5-chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid was reacted with 1-(4-furo[3,2-c]pyridinyl)piperazine as in General Procedure 10 to give the title compound. LCMS: m/z=633.99 (M+H+); retention time=0.64 minutes.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08080561B2
Source dataset	uspto-grants-2011_12
ORD ID	ord-569d676b37634e5a9a28d9a4e34d4d27
Source note	uspto-grants-2011_12