Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 659535Generated: October 30, 2026

1,3-Dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one → HCID 58327786, compound

https://huagongshe.com/reaction/659535

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-Dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-oneHCID 88638—
Reactant4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acidHCID 46906718—
ProductHCID 58327786HCID 58327786—

Reaction Steps

4-{1-[5-chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid was reacted with 1,3-dihydro-1-(4-piperidinyl)benzoimidazol-2-one as in General Procedure 10 to give the title compound. LCMS: m/z=647.03 (M+H+); retention time=0.81 minutes.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08080561B2
Source datasetuspto-grants-2011_12
ORD IDord-a19b3c824902450b91c95e14270eac00
Source noteuspto-grants-2011_12