反应详情

温度

80 °C

To a solution of 2-bromo-1-(3-bromophenyl)ethanone (120 mg, 0.432 mmol) in dioxane (2 mL) was added imidazole (58.8 mg, 0.864 mmol) and the reaction mixture was stirred for 1 h at 80° C. The reaction mixture was concentrated in vacuo and the residue was purified by flash chromatography using MeOH:CH2Cl2 (6:94) as eluent to give the sub-title compound in 68% yield (77.9 mg, 0.293 mmol).

1. concentrationThe reaction mixture was concentrated in vacuo
2. customthe residue was purified by flash chromatography