Potassium Carbonate → HCID 68586237, compound

Participants

Reaction Conditions

Reaction Steps

4.4 g (29.6 mmol) of 5,6,7,8-tetrahydro-2-naphthol, 5.0 g (26.9 mmol) of 4-chloro-2,5-dimethylnitrobenzene and 5.2 g (37.7 mmol) of potassium carbonate are refluxed in 50 ml of N,N-dimethylformamide for 12 h, poured onto ice, stirred at 0° C. for 15 min, and then filtered. The solid is washed with water and hexane and dried under reduced pressure (6.0 g, 98.0% purity, 70.0% yield, log P (pH 2.3)=5.86).

Provenance & Evidence