HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 4-Chloro-6-(4-chlorophenyl)-2-methyl-2H-pyrazolo[3,4-b]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 178479972 | HCID 178479972 | — |
| Product | 4-Chloro-6-(4-chlorophenyl)-2-methyl-2H-pyrazolo[3,4-b]pyridine | HCID 22756849 | — |
Reaction Steps
Following the procedure of Example 2, 37.8 g. of 6-(4-chlorophenyl)-2-methyl-2H-pyrazolo[3,4-b]pyridin-4-ol (0.146 mol.) and 165 ml. of phosphorus oxychloride yield 35.1 g. (86%) of 4-chloro-6-(4-chlorophenyl)-2-methyl-2H-pyrazolo[3,4-b]pyridine, recrystallized from ethanol; m.p. 177°-179°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04129738 |
| Source dataset | uspto-grants-1978_12 |
| ORD ID | ord-38c2499c8df74fc7a2d43f28d154eaf7 |
| Source note | uspto-grants-1978_12 |