Benzyl Alcohol → HCID 58945262, compound

Participants

Reaction Steps

To a solution of 4-amino, 2-nitrophenol (1 mmol), triphenyl phosphine (1.2 mmol) and benzyl alcohol (1.2 mmol) in dry dichloromethane (5 ml) at ambient temperature, under a nitrogen atmosphere, was added a solution of diethyl azodicarboxylate (1.2 mmol) in dry dichloromethane (2 ml). The resultant mixture was stirred at ambient temperature for 18 hr. Evaporation under reduced pressure afforded a gum that was purified by column chromatography (SiO2; diethyl ether) to give 4-benzyloxy-3-nitro-aniline, yield 85%.

Provenance & Evidence