HuagongsheHuagongshe Chemistry Print Report · For research reference only
NADPH → (S)-1-(3,4-Dimethoxyphenyl)propan-2-OL
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | NADPH | HCID 5884 | — |
| Reactant | 2-Propanone, 1-(3,4-dimethoxyphenyl)- | HCID 69896 | — |
| Product | (S)-1-(3,4-Dimethoxyphenyl)propan-2-OL | HCID 10198066 | — |
Reaction Steps
The carbonyl reductases of the present invention can utilize NADPH as a coenzyme, have no alcohol dehydrogenating activity, and reduce 3,4-dimethoxyphenylacetone by utilizing NADPH as a coenzyme to produce 90% ee or more (S)-1-(3,4-dimethoxyphenyl)-2-propanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07083962B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-9738564159bc4fc6bc633e268b9088a2 |
| Source note | uspto-grants-2006_08 |