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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 660024Generated: November 2, 2026

3-chloro-1H-indole-5-carbaldehyde → 4-[4-(3-Chloro-4-formyl-indol-1-yl)-butyl]-piperidine-1-carboxylic acid

https://huagongshe.com/reaction/660024

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-chloro-1H-indole-5-carbaldehydeHCID 82409276—
ReactantHCID 86631460HCID 86631460—
Product4-[4-(3-Chloro-4-formyl-indol-1-yl)-butyl]-piperidine-1-carboxylic acidHCID 86761478—

Reaction Steps

The title compound was prepared using methods analogous to those described for Intermediate 1 from 4-[4-(4-formyl-indol-1-yl)-butyl]-piperidine-1-carboxylic acid tert-butyl ester. MS: mass calcd. for C23H31ClN2O3, 418.20; m/z found, 441.3 [M+Na]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08084466B2
Source datasetuspto-grants-2011_12
ORD IDord-5f3712e5831545109a39077d9c31df95
Source noteuspto-grants-2011_12