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HRID660089

反应详情

EQUATION

反应方程式

HRID 660089 的结构方程式

REACTANTS

反应物

4
结构：O=C(O)C(O)(c1ccccc1)C1CCCC1
HCID98283

α-Cyclopentylmandelic acid

C13H16O3

结构：CC(C(=O)O[C@H]1C[N+]2(CC(=O)Nc3ccon3)CCC1CC2)(c1ccccc1)c1ccccc1.[Br-]
HCID11678278

未命名化合物

结构：O=C(C[N+]12CCC(CC1)[C@@H](O)C2)Nc1ccon1.[Br-]
HCID86627857

未命名化合物

结构：O=C(C[N+]12CCC(CC1)[C@@H](O)C2)Nc1cnccn1.[Br-]
HCID86627863

未命名化合物

2 次

PRODUCTS

生成物

1
结构：O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C(O)(c1ccccc1)C1CCCC1)C2)Nc1cnccn1.[Br-]
HCID11656809

未命名化合物

PROCEDURE

实验过程

This compound is prepared analogously to (R)-3-(2,2-Diphenyl-propionyloxy)-1-(isoxazol-3-ylcarbamoylmethyl)-1-azonia-bicyclo[2.2.2]octane bromide (Example 4), substituting (R)-3-hydroxy-1-(isoxazol-3-ylcarbamoylmethyl)-1-azonia-bicyclo[2.2.2]octane bromide (Intermediate A) with (R)-3-Hydroxy-1-(pyrazin-2-ylcarbamoylmethyl)-1-azonia-bicyclo[2.2.2]octane bromide (Intermediate H) and by replacing 2,2′-diphenylpropionic acid with cyclopentyl-hydroxy-phenyl-acetic acid, yielding the titled compound as a diastereomeric mixture. (M+ 465.4)