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HRID660090

反应详情

EQUATION

反应方程式

HRID 660090 的结构方程式

REACTANTS

反应物

4
结构：O=C(O)C(O)(c1ccccc1)C1CCCCC1
HCID97700

alpha-Cyclohexylmandelic acid

C14H18O3

结构：O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C(O)(c1ccccc1)C1CCCC1)C2)Nc1cnccn1.[Br-]
HCID11656809

未命名化合物

结构：O=C(C[N+]12CCC(CC1)[C@@H](O)C2)Nc1cnccn1.[Br-]
HCID86627863

未命名化合物

结构：O=C(C[N+]12CCC(CC1)[C@@H](O)C2)Nc1ccncn1.[Br-]
HCID86627870

未命名化合物

2 次

PRODUCTS

生成物

1
结构：O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C(O)(c1ccccc1)C1CCCCC1)C2)Nc1ccncn1.[Br-]
HCID11584887

未命名化合物

PROCEDURE

实验过程

This compound is prepared analogously to (R)-3-(2-Cyclopentyl-2-hydroxy-2-phenyl-acetoxy)-1-(pyrazin-2-ylcarbamoylmethyl)-1-azonia-bicyclo[2.2.2]octane bromide (Example 15) by replacing (R)-3-Hydroxy-1-(pyrazin-2-ylcarbamoylmethyl)-1-azonia-bicyclo-[2.2.2]octane bromide (Intermediate H) with (R)-3-Hydroxy-1-(pyrimidin-4-ylcarbamoyl-methyl)-1-azonia-bicyclo[2.2.2]octane bromide (Intermediate Q) and by replacing cyclopentyl-hydroxy-phenyl-acetic acid with cyclohexyl-hydroxy-phenyl-acetic acid, yielding the titled compound as a diastereomeric mixture. (M+ 479.5).