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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 660119Generated: November 1, 2026

HCID 66657281, compound → HCID 66657263, compound

https://huagongshe.com/reaction/660119

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66657281HCID 66657281—
SolventEthanol hydrochlorideHCID 21887872—
ProductHCID 66657263HCID 66657263272%

Reaction Steps

3(S)-[(3,4-dichlorophenyl)phenylamino]pyrrolidine-1-carboxylic acid tert-butyl ester (0.13 g) was dissolved in 1 N hydrochloric acid-ethanol and heated under reflux for one hour. The reaction solution was concentrated to dryness to thereby obtain 0.11 g of brown amorphous solid 3(S)-(3,4-dichlorophenyl)phenylpyrrolidin-3-ylamine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08084442B2
Source datasetuspto-grants-2011_12
ORD IDord-2673c710b5f04813bb493e9513b4688a
Source noteuspto-grants-2011_12