Diethyl disulfide → HCID 178477306, compound

HRID 660147Notes

Reaction equation

HRID 660147 reaction equation
[CH3:1][S:2][C:3]1[C:4]([C:8]2[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=2)=[N:5][NH:6][CH:7]=1.[CH2:14](SSCC)C.BrC1C(C2C=NC=CC=2)=NNC=1>>[CH2:1]([S:2][C:3]1[C:4]([C:8]2[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=2)=[N:5][NH:6][CH:7]=1)[CH3:14]

Participants

4

Reactant 3

HCID 8077Diethyl disulfideHCID 178419464HCID 178419464, compound2×HCID 178503312HCID 178503312, compound

Product 1

HCID 178477306HCID 178477306, compoundYield 76%

Procedure

Compound 21D was prepared following the procedure as described for the synthesis of compound 21A (see Scheme 3) using ethyldisulfanyl-ethane as the disulfide and 3-(4-bromo-1H-pyrazol-3-yl)-pyridine (compound 20A).

Sources & evidence

ORD record
ord-3094ccd67c1147a99d73b01512d4661e
Source dataset
uspto-grants-2011_12
Patent number
US08084473B2

Reaction notes

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