HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formic Acid → N-Pyridin-2-ylmethyl-formamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formic Acid | HCID 284 | — |
| Reactant | 2-Pyridinemethanamine | HCID 19509 | — |
| Product | N-Pyridin-2-ylmethyl-formamide | HCID 12228441 | — |
Reaction Steps
A mixture of 32.4 g. of 2-aminomethylpyridine and 96 ml. of 97% formic acid is heated under reflux for 3.5 hrs. The resulting solution is subjected to vacuum distillation, the desired product being isolated as the fraction boiling at 120° C./0.03 mm, 37.3 g. The product which is isolated as a yellow oil crystallized to a solid having a melting point at about room temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04129567 |
| Source dataset | uspto-grants-1978_12 |
| ORD ID | ord-4c9dfbe434ad493aa3a7209d2dc84df3 |
| Source note | uspto-grants-1978_12 |