Propyl mercaptan → HCID 178460779, compound

HRID 660174Notes

Reaction equation

HRID 660174 reaction equation
[CH2:1]([S:6][C:7]1[C:8]([CH:12]2[CH:17]3[CH2:18][CH2:19][N:14]([CH2:15][CH2:16]3)[CH2:13]2)=[N:9][NH:10][CH:11]=1)[CH2:2][CH2:3]CC.C(S)CC>>[CH2:1]([S:6][C:7]1[C:8]([CH:12]2[CH:17]3[CH2:18][CH2:19][N:14]([CH2:15][CH2:16]3)[CH2:13]2)=[N:9][NH:10][CH:11]=1)[CH2:2][CH3:3]

Participants

3

Reactant 2

HCID 7848Propyl mercaptanHCID 178447695HCID 178447695, compound

Product 1

HCID 178460779HCID 178460779, compoundYield 25%

Procedure

Compound 49E was prepared following the procedure as described for the synthesis of compound 49B (see Scheme 10) using propane-1-thiol as reagent. Subsequent purification by flash chromatography (EtOH to EtOH/triethylamine 99/1) afforded compound 49E.

Workup

  1. customSubsequent purification by flash chromatography (EtOH to EtOH/triethylamine 99/1)

Sources & evidence

ORD record
ord-909923f880864786aec964dfb6b4635d
Source dataset
uspto-grants-2011_12
Patent number
US08084473B2

Reaction notes

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