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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 660213Generated: October 29, 2026

(S)-Methyl 4-(1-aminoethyl)benzoate hydrochloride → Methyl 4-[(1S)-1-({5-chloro-2-[(2,4-difluorophenoxy)methyl]benzoyl}amino)ethyl]benzoate

https://huagongshe.com/reaction/660213

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-Methyl 4-(1-aminoethyl)benzoate hydrochlorideHCID 57462942—
ReactantHCID 68863578HCID 68863578—
ProductMethyl 4-[(1S)-1-({5-chloro-2-[(2,4-difluorophenoxy)methyl]benzoyl}amino)ethyl]benzoateHCID 68866197—

Reaction Steps

The title compound was prepared according to the procedure described in step 6 of Example 1 from 5-chloro-2-[(2,4-difluorophenoxy)methyl]benzoic acid (step 2) and methyl 4-[(1S)-1-aminoethyl]benzoate hydrochloride (step 5 of Example 1):

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08084476B2
Source datasetuspto-grants-2011_12
ORD IDord-2e35106405824d6ba38d0d68e659cdc2
Source noteuspto-grants-2011_12