(S)-Methyl 4-(1-aminoethyl)benzoate hydrochloride → HCID 68863748, compound

HRID 660229Notes

Reaction equation

HRID 660229 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:11][O:12][CH:13]2[CH2:17][CH2:16][CH2:15][CH2:14]2)=[C:6]([CH:10]=1)[C:7]([OH:9])=O.Cl.[NH2:19][C@H:20]([C:22]1[CH:31]=[CH:30][C:25]([C:26]([O:28][CH3:29])=[O:27])=[CH:24][CH:23]=1)[CH3:21]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:11][O:12][CH:13]2[CH2:17][CH2:16][CH2:15][CH2:14]2)=[C:6]([CH:10]=1)[C:7]([NH:19][C@H:20]([C:22]1[CH:31]=[CH:30][C:25]([C:26]([O:28][CH3:29])=[O:27])=[CH:24][CH:23]=1)[CH3:21])=[O:9]

Participants

3

Reactant 2

HCID 57462942(S)-Methyl 4-(1-aminoethyl)benzoate hydrochlorideHCID 688635365-Chloro-2-[(cyclopentyloxy)methyl]benzoic acid

Product 1

HCID 68863748HCID 68863748, compound

Procedure

The title compound was prepared according to the procedure described in step 6 of Example 1 from 5-chloro-2-[(cyclopentyloxy)methyl]benzoic acid (step 1) and methyl 4-[(1S)-1-aminoethyl]benzoate hydrochloride (step 5 of Example 1):

Sources & evidence

ORD record
ord-df5d4ae122e54fd495906f2702aef9cf
Source dataset
uspto-grants-2011_12
Patent number
US08084476B2

Reaction notes

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