(S)-Methyl 4-(1-aminoethyl)benzoate hydrochloride → HCID 68864365, compound

HRID 660236Notes

Reaction equation

HRID 660236 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:11][O:12][C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([NH:21][CH3:22])=[O:20])[CH:14]=2)=[C:6]([CH:10]=1)[C:7]([OH:9])=O.Cl.[NH2:24][C@H:25]([C:27]1[CH:36]=[CH:35][C:30]([C:31]([O:33][CH3:34])=[O:32])=[CH:29][CH:28]=1)[CH3:26]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:11][O:12][C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([NH:21][CH3:22])=[O:20])[CH:14]=2)=[C:6]([CH:10]=1)[C:7]([NH:24][C@H:25]([C:27]1[CH:36]=[CH:35][C:30]([C:31]([O:33][CH3:34])=[O:32])=[CH:29][CH:28]=1)[CH3:26])=[O:9]

Participants

3

Reactant 2

HCID 57462942(S)-Methyl 4-(1-aminoethyl)benzoate hydrochlorideHCID 68863169HCID 68863169, compound

Product 1

HCID 68864365HCID 68864365, compound

Procedure

The title compound was prepared according to the procedure described in step 6 of Example 1 from 5-chloro-2-({3-[(methylamino)carbonyl]phenoxy}methyl)benzoic acid (step 2) and methyl 4-[(1S)-1-aminoethyl]benzoate hydrochloride (step 3 of Example 1):

Sources & evidence

ORD record
ord-bd934c101cd94deb880d0f2b23b985ac
Source dataset
uspto-grants-2011_12
Patent number
US08084476B2

Reaction notes

Loading…