(S)-Methyl 4-(1-aminoethyl)benzoate hydrochloride → HCID 68863396, compound

HRID 660244Notes

Reaction equation

HRID 660244 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:11][N:12]([C:14]2[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][N:15]=2)[CH3:13])=[C:6]([CH:10]=1)[C:7]([OH:9])=O.Cl.[NH2:22][C@H:23]([C:25]1[CH:34]=[CH:33][C:28]([C:29]([O:31][CH3:32])=[O:30])=[CH:27][CH:26]=1)[CH3:24]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:11][N:12]([C:14]2[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][N:15]=2)[CH3:13])=[C:6]([CH:10]=1)[C:7]([NH:22][C@H:23]([C:25]1[CH:34]=[CH:33][C:28]([C:29]([O:31][CH3:32])=[O:30])=[CH:27][CH:26]=1)[CH3:24])=[O:9]

Participants

3

Reactant 2

HCID 57462942(S)-Methyl 4-(1-aminoethyl)benzoate hydrochlorideHCID 68864334HCID 68864334, compound

Product 1

HCID 68863396HCID 68863396, compound

Procedure

The title compound was prepared according to the procedure described in step 6 of Example 1 from 5-chloro-2-{[(5-chloropyridin-2-yl)(methyl)amino]methyl}benzoic acid (step 2) and methyl 4-[(1S)-1-aminoethyl]benzoate hydrochloride (step 5 of Example 1):

Sources & evidence

ORD record
ord-5f97831a3a0a4a338bee4111f8d77f44
Source dataset
uspto-grants-2011_12
Patent number
US08084476B2

Reaction notes

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