反应详情

2-(4-Hydroxy-phenyl)-propionic acid (788 mg, 1 mmol) in CH3COOH (10 ml) is added to 60% Nitric acid (552 mg, 1.11 mmol) at room temperature. The reaction mixture is stirred for 1 h. The iced water (50 ml) added to the reaction mixture. The mixture is extracted with ethyl acetate. The extracts are washed with water, dried over magnesium sulfate, filtered and concentrated in vacuo.

1. extractionThe mixture is extracted with ethyl acetate
2. washThe extracts are washed with water
3. dry with materialdried over magnesium sulfate
4. filtrationfiltered
5. concentrationconcentrated in vacuo