HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → N-[4-(1-Cyanoethyl)phenyl]acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 2-(4-Aminophenyl)propiononitrile | HCID 120011 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | N-[4-(1-Cyanoethyl)phenyl]acetamide | HCID 12226815 | — |
Reaction Steps
A solution of 2-(4-Amino-phenyl)-propionitrile (10.2 g, 69.8 mmol) in pyridine (40 mL) was added Ac2O (7.49 g, 73.4 mmol) at room temperature. The reaction mixture was refluxed for 1 hrs then cooled to room temperature, and concentrated in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08084484B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-e4ec7258821f44eebb22c09917403a21 |
| Source note | uspto-grants-2011_12 |