HCID 68843096, compound → HCID 68994518, compound

HRID 660502Notes

Reaction equation

HRID 660502 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8][C:9](=O)/[CH:10]=[CH:11]/[C:12]1[CH:17]=[CH:16][C:15]([N:18]2[CH2:22][C:21](=[O:23])[NH:20][S:19]2(=[O:25])=[O:24])=[C:14]([O:26][CH2:27][C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[CH:13]=1>C(O)(=O)C>[NH:1]1[C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[N:8]=[C:9]1/[CH:10]=[CH:11]/[C:12]1[CH:17]=[CH:16][C:15]([N:18]2[S:19](=[O:25])(=[O:24])[NH:20][C:21](=[O:23])[CH2:22]2)=[C:14]([O:26][CH2:27][C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[CH:13]=1

Participants

3

Reactant 1

HCID 68843096HCID 68843096, compound

Product 1

HCID 68994518HCID 68994518, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of (E)-N-(2-aminophenyl)-3-[3-benzyloxy-4-(1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)-phenyl]-acrylamide in acetic acid is stirred at 60° C. for 18 h. The solvent is removed under reduced pressure to give the title compound.

Workup

  1. customThe solvent is removed under reduced pressure

Sources & evidence

ORD record
ord-f7934a2b01e64440b28c9583339ca913
Source dataset
uspto-grants-2011_12
Patent number
US08084448B2

Reaction notes

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