Triphenylphosphine → 2-Ethoxycarbonylbenzyltriphenylphosphonium bromide

Participants

Reaction Steps

A mixture of 2-bromomethylbenzoic acid ethyl ester (25 g, 102.8 mmol) and triphenylphosphine (32.4 g, 123.5 mmol) in toluene is refluxed for 1 h. The solution is cooled to RT and filtered to afford the title compound as a brown solid: (M+1)+=243, 245.

Provenance & Evidence