Trifluoroacetic acid → HCID 68996297, compound

Participants

Reaction Steps

To a solution of ((S)-1-benzyl-2-{3-benzyloxy-4-[1,1,4-trioxo-5-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-2-yl]-phenyl}-ethyl)-carbamic acid tert-butyl ester (intermediate from Example 60) (510 mg, 0.78 mmol) in methylene chloride (5 mL) is added TFA (2 mL) and the mixture is stirred at RT for 5 h. The solvent is removed under reduced pressure to give the title compound. This material is used directly in the next reaction.

Provenance & Evidence