tert-Butyl N-(4-hydroxybutyl)carbamate → 2-(4-tert-Butoxycarbonylaminobutoxy)-6-hydroxybenzoic Acid Benzyl Ester

HRID 660613Notes

Reaction equation

HRID 660613 reaction equation
[CH2:1]([O:8][C:9](=[O:18])[C:10]1[C:15]([OH:16])=[CH:14][CH:13]=[CH:12][C:11]=1[OH:17])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:19]([NH:26][CH2:27][CH2:28][CH2:29][CH2:30]O)([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20]>>[CH2:1]([O:8][C:9](=[O:18])[C:10]1[C:11]([OH:17])=[CH:12][CH:13]=[CH:14][C:15]=1[O:16][CH2:30][CH2:29][CH2:28][CH2:27][NH:26][C:19]([O:21][C:22]([CH3:23])([CH3:25])[CH3:24])=[O:20])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 545141tert-Butyl N-(4-hydroxybutyl)carbamateHCID 10586364Benzyl 2,6-dihydroxybenzoate

Product 1

HCID 688425912-(4-tert-Butoxycarbonylaminobutoxy)-6-hydroxybenzoic Acid Benzyl Ester

Procedure

The title compound is prepared from 2,6-dihydroxybenzoic acid benzyl ester and 4-(Boc-amino)-1-butanol analogous to Example 1109 step A.

Sources & evidence

ORD record
ord-112389abe34144b991e1f072bf4d9cdd
Source dataset
uspto-grants-2011_12
Patent number
US08084448B2

Reaction notes

Loading…