Sodium Sulfate → (2,6-Bis-benzyloxyphenyl)-methanol

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Reaction Steps

To a solution of 2,6-bis-benzyloxybenzoic acid benzyl ester (3.0 g, 6.6 mmol) in THF (15 mL) at 0° C. is added dropwise 7.92 mL of LiAlH4 (1.0M in THF) then the mixture is stirred at RT for 18 h. Saturated sodium sulfate solution (1 ml) is added carefully and the resulting precipitate is filtered. The filtrate is evaporated to give the title compound. This is used directly in the next reaction.

Provenance & Evidence