tert-Butyl methacrylate → HCID 57777407, compound

HRID 660642Notes

Reaction equation

HRID 660642 reaction equation
C([O:8][C:9]1[CH:14]=[C:13](I)[CH:12]=[CH:11][C:10]=1[N:16]1[S:20](=[O:22])(=[O:21])[N:19](CC[Si](C)(C)C)[C:18](=[O:29])[CH2:17]1)C1C=CC=CC=1.[C:30]([O:35][C:36]([CH3:39])([CH3:38])[CH3:37])(=[O:34])[C:31]([CH3:33])=[CH2:32]>>[C:36]([O:35][C:30](=[O:34])[CH:31]([CH3:33])[CH2:32][C:13]1[CH:12]=[CH:11][C:10]([N:16]2[CH2:17][C:18](=[O:29])[NH:19][S:20]2(=[O:21])=[O:22])=[C:9]([OH:8])[CH:14]=1)([CH3:39])([CH3:38])[CH3:37]

Participants

3

Reactant 2

HCID 11448tert-Butyl methacrylateHCID 667569375-(2-Benzyloxy-4-iodophenyl)-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one

Product 1

HCID 57777407HCID 57777407, compound

Procedure

The title compound is prepared from 5-(2-benzyloxy-4-iodophenyl)-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one and t-butyl methacrylate analogous to Example 133 with the modification that the TMS-ethyl group is removed after the Heck reaction.

Workup

  1. customis removed
  2. customafter the Heck reaction

Sources & evidence

ORD record
ord-30a895d1743c450295a45da281da7ea0
Source dataset
uspto-grants-2011_12
Patent number
US08084448B2

Reaction notes

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