HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonyl chloride → 5-{2-Benzyloxy-4-[(E)-2-(1-methanesulfonylpiperidin-2-yl)-vinyl]-phenyl}-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | HCID 68842724 | HCID 68842724 | — |
| Product | 5-{2-Benzyloxy-4-[(E)-2-(1-methanesulfonylpiperidin-2-yl)-vinyl]-phenyl}-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one | HCID 68839841 | — |
Reaction Steps
The title compound is prepared from 5-[2-benzyloxy-4-((E)-2-piperidin-2-yl-vinyl)-phenyl]-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one (Example 92, step A) and methanesulfonyl chloride analogous to Example 192, step B.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08084448B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-f1eb428496fe41e9ab29c1a8fcd5d532 |
| Source note | uspto-grants-2011_12 |