HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenesulfonyl chloride → 5-{4-[2-(1-Benzenesulfonylpiperidin-2-yl)-ethyl]-2-hydroxyphenyl}-1,1-dioxo-1,2,5-thiadiazolidin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenesulfonyl chloride | HCID 7369 | — |
| Reactant | HCID 68842724 | HCID 68842724 | — |
| Product | 5-{4-[2-(1-Benzenesulfonylpiperidin-2-yl)-ethyl]-2-hydroxyphenyl}-1,1-dioxo-1,2,5-thiadiazolidin-3-one | HCID 57777333 | — |
Reaction Steps
The title compound is prepared from 5-[2-benzyloxy-4-(E)-2-piperidin-2-yl-vinyl)-phenyl]-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one (Example 92, step A) and benzenesulfonyl chloride analogous to Example 193: LC retention time=1.28 min (Method A); (M−1)−=478.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08084448B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-4d9d956409f044a68a511ad6f43127f4 |
| Source note | uspto-grants-2011_12 |