tert-Butyl 3-ethenylpyrrolidine-1-carboxylate → HCID 68999552, compound

HRID 660657Notes

Reaction equation

HRID 660657 reaction equation
[CH2:1]([O:8][C:9]1[CH:14]=[C:13](I)[CH:12]=[CH:11][C:10]=1[N:16]1[S:20](=[O:22])(=[O:21])[N:19]([CH2:23][CH2:24][Si:25]([CH3:28])([CH3:27])[CH3:26])[C:18](=[O:29])[CH2:17]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:30]([O:34][C:35]([N:37]1[CH2:41][CH2:40][CH:39]([CH:42]=[CH2:43])[CH2:38]1)=[O:36])([CH3:33])([CH3:32])[CH3:31]>>[C:30]([O:34][C:35]([N:37]1[CH2:41][CH2:40][CH:39](/[CH:42]=[CH:43]/[C:13]2[CH:12]=[CH:11][C:10]([N:16]3[CH2:17][C:18](=[O:29])[N:19]([CH2:23][CH2:24][Si:25]([CH3:28])([CH3:27])[CH3:26])[S:20]3(=[O:22])=[O:21])=[C:9]([O:8][CH2:1][C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)[CH:14]=2)[CH2:38]1)=[O:36])([CH3:33])([CH3:32])[CH3:31]

Participants

3

Reactant 2

HCID 53302213tert-Butyl 3-ethenylpyrrolidine-1-carboxylateHCID 667569375-(2-Benzyloxy-4-iodophenyl)-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one

Product 1

HCID 68999552HCID 68999552, compound

Procedure

The title compound is prepared from 5-(2-benzyloxy-4-iodophenyl)-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one and 3-vinylpyrrolidine-1-carboxylic acid tert-butyl ester analogous to Example 62, step B.

Sources & evidence

ORD record
ord-ab89f8d91bda4120b1270d129d19eff1
Source dataset
uspto-grants-2011_12
Patent number
US08084448B2

Reaction notes

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