Triethylamine → HCID 68838003, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 3-vinyl-[1,2]thiazinane 1,1-dioxide (107 mg, 0.664 mmol) (J. Org. Chem. 69, 6377 (2004)), 5-(2-benzyloxy-4-iodophenyl)-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one (250 mg, 0.563 mmol), Pd(OAc)2 (13 mg, 0.058 mmol) and triethylamine (0.768 mL, 5.51 mmol) in MeCN (4 mL) is heated at 120° C. for 1.5 h in a microwave apparatus. The reaction mixture is concentrated and the residue purified by preparative HPLC to afford the title compound.

Provenance & Evidence