HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Benzyl-3-(3-benzyloxy-4-nitrophenyl)-1-phenylpropan-1-one → 3-(4-Amino-3-benzyloxyphenyl)-1,2-diphenylpropan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Benzyl-3-(3-benzyloxy-4-nitrophenyl)-1-phenylpropan-1-one | HCID 68838918 | — |
| Catalyst | Platinum | HCID 23939 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3-(4-Amino-3-benzyloxyphenyl)-1,2-diphenylpropan-1-one | HCID 68839177 | — |
Reaction Steps
A solution of 2-benzyl-3-(3-benzyloxy-4-nitrophenyl)-1-phenylpropan-1-one (200 mg) in EtOAc (5 mL) is hydrogenated over 5% Pt/C (15 mg) at 1 atm for 18 h. The catalyst is filtered and the filtrate evaporated to give the title compound as a gum: (M+1)+=422.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08084448B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-77e72605930f44e7913e2a09c7948d63 |
| Source note | uspto-grants-2011_12 |