HCID 68843025, compound → HCID 57777365, compound

Participants

Reaction Steps

To a solution of 5-[2-benzyloxy-4-(2-methyl-3-oxo-3-phenylpropyl)-phenyl]-1,1-dioxo-1,2,5-thiadiazolidin-3-one potassium salt (Example 246, step C) in 5 mL of EtOH/water (1:1)) is added 15 mg of Degussa Pd/C and the resulting mixture is hydrogenated at 1 atm for 4 h. The catalyst is filtered through Celite and the solvent is removed under reduced pressure. The residue is purified by preparative HPLC to give the title compound: (M−1)−=375.

Provenance & Evidence