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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 660757Generated: October 28, 2026

5-(2-Benzyloxy-4-iodophenyl)-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one → 4-{3-Benzyloxy-4-[1,1,4-trioxo-5-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-2-yl]-phenyl}-3,3-dimethylbutyronitrile

https://huagongshe.com/reaction/660757

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(2-Benzyloxy-4-iodophenyl)-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-oneHCID 66756937—
Reactant4-Iodo-3,3-dimethyl-butyronitrileHCID 86632587—
Product4-{3-Benzyloxy-4-[1,1,4-trioxo-5-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-2-yl]-phenyl}-3,3-dimethylbutyronitrileHCID 68922346—

Reaction Steps

The title compound is prepared 5-(2-benzyloxy-4-iodophenyl)-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one and 4-iodo-3,3-dimethylbutyronitrile analogous to Example 292, step A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08084448B2
Source datasetuspto-grants-2011_12
ORD IDord-4f882595142c4452af6b845e031dd849
Source noteuspto-grants-2011_12