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HRID660764

反应详情

EQUATION

反应方程式

HRID 660764 的结构方程式

REACTANTS

反应物

1
结构：COC(=O)CN(c1ccc(OCC(=O)OCC[Si](C)(C)C)cc1OCc1ccccc1)S(=O)(=O)NC(=O)OC(C)(C)C
HCID68997226

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)CN(c1ccc(OCC(=O)OCC[Si](C)(C)C)cc1OCc1ccccc1)S(N)(=O)=O
HCID68840538

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1COCCO1.Cl
溶剂HCID20443148

1,4-Dioxane hydrochloride

C4H9ClO2

PROCEDURE

实验过程

A mixture of methyl N-(2-(benzyloxy)-4-{2-oxo-2-[2-(trimethylsilyl)ethoxy]ethoxy}phenyl)-N-{[(tert-butoxycarbonyl)amino]sulfonyl}glycinate (50 mg, 0.08 mmol) in HCl/dioxane (3 mL, 4.0 M) is stirred at RT for 30 min. The solvent is removed under reduced pressure and water is added. The mixture is extracted with EtOAc and the organic phase dried over magnesium sulfate. The solvent is removed under reduced pressure to give the title compound.

WORKUP

后处理

  1. customThe solvent is removed under reduced pressure and water
  2. additionis added
  3. extractionThe mixture is extracted with EtOAc
  4. dry with materialthe organic phase dried over magnesium sulfate
  5. customThe solvent is removed under reduced pressure