HRID660791

反应详情

EQUATION

反应方程式

REACTANTS

反应物

反应SMILES：COc1ccc(COc2ccc(C)cc2Cc2ccc(N3CC(=O)N(CC[Si](C)(C)C)S3(=O)=O)c(OCc3ccccc3)c2)cc1

HCID68842258

未命名化合物

PRODUCTS

产物

反应SMILES：Cc1ccc(O)c(Cc2ccc(N3CC(=O)N(CC[Si](C)(C)C)S3(=O)=O)c(OCc3ccccc3)c2)c1

HCID66756551

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID21863450

未命名化合物

PROCEDURE

实验过程

A solution of 5-{2-benzyloxy-4-[2-(4-methoxybenzyloxy)-5-methylbenzyl]-phenyl}-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one (50 mg) in 10% TFA/methylene chloride (1 mL) is stirred at RT for 2 h. The solvent is removed under reduced pressure to give the title compound.

WORKUP

后处理

customThe solvent is removed under reduced pressure

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-b490be87810a44b2a68ec658df0013a9
来源数据集: uspto-grants-2011_12
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US08084448B2
来源说明: uspto-grants-2011_12

反应SMILES

[CH2:1]([O:8][C:9]1[CH:14]=[C:13]([CH2:15][C:16]2[CH:21]=[C:20]([CH3:22])[CH:19]=[CH:18][C:17]=2[O:23]CC2C=CC(OC)=CC=2)[CH:12]=[CH:11][C:10]=1[N:33]1[S:37](=[O:39])(=[O:38])[N:36]([CH2:40][CH2:41][Si:42]([CH3:45])([CH3:44])[CH3:43])[C:35](=[O:46])[CH2:34]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(O)(C(F)(F)F)=O.C(Cl)Cl>[CH2:1]([O:8][C:9]1[CH:14]=[C:13]([CH2:15][C:16]2[CH:21]=[C:20]([CH3:22])[CH:19]=[CH:18][C:17]=2[OH:23])[CH:12]=[CH:11][C:10]=1[N:33]1[S:37](=[O:39])(=[O:38])[N:36]([CH2:40][CH2:41][Si:42]([CH3:43])([CH3:45])[CH3:44])[C:35](=[O:46])[CH2:34]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1