HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylpiperidine → 5-(2-Hydroxy-4-{2-[2-(4-methylpiperidin-1-yl)-2-oxo-ethyl]-benzyl}-phenyl)-1,1-dioxo-1,2,5-thiadiazolidin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylpiperidine | HCID 69381 | — |
| Reactant | {2-[3-Benzyloxy-4-(1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)-benzyl]-phenyl}-acetic Acid | HCID 68839879 | — |
| Product | 5-(2-Hydroxy-4-{2-[2-(4-methylpiperidin-1-yl)-2-oxo-ethyl]-benzyl}-phenyl)-1,1-dioxo-1,2,5-thiadiazolidin-3-one | HCID 57777356 | — |
Reaction Steps
The title compound is prepared from {2-[3-benzyloxy-4-(1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)-benzyl]-phenyl}-acetic acid and 4-methylpiperidine analogous to Example 314, steps B and C. (M−1)−=456. HPLC retention time=1.07 min (Method A).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08084448B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-049247e34a3940fd8dca426479b6edcc |
| Source note | uspto-grants-2011_12 |