Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 660979Generated: October 30, 2026

2-Chloro-5-hydroxypyridine → 6-[4-(Trifluoromethyl)phenyl]pyridin-3-ol

https://huagongshe.com/reaction/660979

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-hydroxypyridineHCID 819821—
Reactant4-(Trifluoromethyl)phenylboronic acidHCID 2734389—
Product6-[4-(Trifluoromethyl)phenyl]pyridin-3-olHCID 53229525—

Reaction Steps

The titled compound is made in a manner substantially similar to Preparation 28 starting from the 6-chloro-pyridin-3-ol and 4-trifluoromethylphenyl boronic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08084489B2
Source datasetuspto-grants-2011_12
ORD IDord-2e71052737394b5eb0cd136febf453cb
Source noteuspto-grants-2011_12