Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | 5-Bromo-2-fluorobenzonitrile | HCID 2724900 | — |
| Product | 3-Amino-5-bromo-1H-indazole | HCID 817910 | 99.5% |
Reaction Steps
To a 250 mL round-bottom flask was added 5-bromo-2-fluorobenzonitrile (15.54 g, 77.7 mmol) and hydrazine (124 g, 3885 mmol). The reaction mixture was heated to 100° C. for 5 minutes. The hydrazine was then removed under reduced pressure to give 5-bromo-1H-indazol-3-amine (16.4 g, 99.5% yield). MS m/z: 213 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08084479B2 |
|---|
| Source dataset | uspto-grants-2011_12 |
|---|
| ORD ID | ord-1aeeede6f2ab47b0aa89f0d2fed652e8 |
|---|
| Source note | uspto-grants-2011_12 |
|---|
