HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chloroperbenzoic acid → {3-(3-Isopropoxy-1,2,4-oxadiazol-5-yl)-5-[4-(trifluoromethoxy)phenyl]piperidin-1-yl}(1-oxidothiomorpholin-4-yl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | {3-(3-Isopropoxy-1,2,4-oxadiazol-5-yl)-5-[4-(trifluoromethoxy)phenyl]piperidin-1-yl}(thiomorpholin-4-yl)methanone | HCID 49819701 | — |
| Product | {3-(3-Isopropoxy-1,2,4-oxadiazol-5-yl)-5-[4-(trifluoromethoxy)phenyl]piperidin-1-yl}(1-oxidothiomorpholin-4-yl)methanone | HCID 58116498 | — |
Reaction Steps
170 mg (0.340 mmol) of the compound from Example 33 were reacted according to General Method 2 with 117 mg (0.340 mmol) of meta-chloroperbenzoic acid. Yield: 44.8 mg (26% of theory).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08084469B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-705e916a0d73404b87a32faa18b3c5bf |
| Source note | uspto-grants-2011_12 |