HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chloroperbenzoic acid → {3-[3-(2-Methoxyethoxy)-1,2,4-oxadiazol-5-yl]-5-[4-(2,2,2-trifluoroethyl)phenyl]piperidin-1-yl}-(1-oxidothiomorpholin-4-yl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | {3-[3-(2-Methoxyethoxy)-1,2,4-oxadiazol-5-yl]-5-[4-(2,2,2-trifluoroethyl)phenyl]piperidin-1-yl}-(thiomorpholin-4-yl)methanone | HCID 58116571 | — |
| Product | {3-[3-(2-Methoxyethoxy)-1,2,4-oxadiazol-5-yl]-5-[4-(2,2,2-trifluoroethyl)phenyl]piperidin-1-yl}-(1-oxidothiomorpholin-4-yl)methanone | HCID 58116466 | — |
Reaction Steps
46.7 mg (0.091 mmol) of the compound from Example 70 were reacted according to General Method 2 with 28.2 mg (0.082 mmol) of meta-chloroperbenzoic acid. Yield: 52.8 mg (100% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08084469B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-f0283a71a5b64b9ba52f2c46a1508157 |
| Source note | uspto-grants-2011_12 |