m-Chloroperbenzoic acid → {3-(3-Ethoxy-1,2,4-oxadiazol-5-yl)-5-[3-fluoro-4-(2,2,2-trifluoroethyl)phenyl]piperidin-1-yl}(1-oxidothiomorpholin-4-yl)methanone

Participants

Role	Name	HCID	Charge
Reactant	m-Chloroperbenzoic acid	HCID 70297	—
Reactant	{3-(3-Ethoxy-1,2,4-oxadiazol-5-yl)-5-[3-fluoro-4-(2,2,2-trifluoroethyl)phenyl]piperidin-1-yl}-(thiomorpholin-4-yl)methanone	HCID 58116525	—
Product	{3-(3-Ethoxy-1,2,4-oxadiazol-5-yl)-5-[3-fluoro-4-(2,2,2-trifluoroethyl)phenyl]piperidin-1-yl}(1-oxidothiomorpholin-4-yl)methanone	HCID 58116507	—

Reaction Steps

76.0 mg (0.151 mmol) of the compound from Example 77 were reacted according to General Method 2 with 47.0 mg (0.136 mmol) of meta-chloroperbenzoic acid. Yield: 60.5 mg (77% of theory)

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08084469B2
Source dataset	uspto-grants-2011_12
ORD ID	ord-d82e1b331fcd47b3b289586a72baf650
Source note	uspto-grants-2011_12