HCID 58116564, compound → HCID 58116534, compound

HRID 661315Notes

Reaction equation

HRID 661315 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[CH:4][C:3]=1[CH:12]1[CH2:17][N:16]([C:18]([N:20]2[CH2:25][CH2:24][S:23][CH2:22][CH2:21]2)=[O:19])[CH2:15][CH:14]([C:26](O)=[O:27])[CH2:13]1.O[N:30]=[C:31]([O:33][CH2:34][CH3:35])[NH2:32]>>[CH2:34]([O:33][C:31]1[N:32]=[C:26]([CH:14]2[CH2:13][CH:12]([C:3]3[CH:4]=[CH:5][C:6]([C:8]([F:11])([F:10])[F:9])=[CH:7][C:2]=3[F:1])[CH2:17][N:16]([C:18]([N:20]3[CH2:25][CH2:24][S:23][CH2:22][CH2:21]3)=[O:19])[CH2:15]2)[O:27][N:30]=1)[CH3:35]

Participants

3

Reactant 2

HCID 58116564HCID 58116564, compoundHCID 76223295ethyl N-hydroxyimidocarbamate

Product 1

HCID 58116534HCID 58116534, compound

Procedure

According to General Method 4, 254 mg (0.405 mmol) of the compound from Example 90A and 63 mg (0.607 mmol) of ethyl N′-hydroxyimidocarbamate [G. Zinner, G. Nebel, Arch. Pharm. 1970, 303, 385-390] were reacted. Yield: 70 mg (35% of theory).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-55d698d7ac5843c494834bb0fe083514
Source dataset
uspto-grants-2011_12
Patent number
US08084469B2

Reaction notes

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