Trifluoroacetic acid → HCID 42600592, compound

Participants

Reaction Steps

The title compound was prepared using the procedure as described in Example 1E, except for substituting 4-(trifluoromethylsulfonyl)aniline for 4-(trifluoromethyl)aniline, and substituting the product of Example 7C for the product of Example 1D. 1H NMR (300 MHz, DMSO-d6) δ ppm 2.21-2.44 (m, 4H), 2.90 (s, 2H), 2.96 (s, 3H), 6.81 (t, J=3.90 Hz, 1H), 7.42 (dd, J=8.14, 4.41 Hz, 1H), 7.95 (dd, J=7.97, 1.52 Hz, 1H), 8.06 (d, J=9.16 Hz, 2H), 8.14 (d, J=9.16 Hz, 2H), 8.53 (dd, J=4.75, 1.35 Hz, 1H), 10.39 (s, 1H). MS (ESI) m/z 475.02 (M+H)+. Calcd for C20H18ClF3N2O4S.0.16 TFA: C, 49.49, H, 3.71, N, 5.68; Found: C, 49.57, H, 3.57, N, 5.42.

Provenance & Evidence